Purification of a fraction of MDM2 for manufacturing of polyclonal antisera.
A histidine-tagged, carboxy-terminal fragment of the murine double minute 2 gene product, p90(MDM2), was purified by Ni–NTA chromatography and preparative gel electrophoresis. The purified MDM2 fragment was used to generate polyclonal antisera that acknowledge a number of species of MDM2 proteins, together with the inhibitor of p53, p90(MDM2), in addition to the activator of p53, p76(MDM2). The antibodies are helpful for Western evaluation, immunoprecipitation, and immunofluorescence.
Autoantibody to MDM2: A Potential Serological Marker of Systemic Lupus Erythematosus.
Introduction. Systemic lupus erythematosus (SLE) is without doubt one of the systemic autoimmune illnesses characterised by the polyclonal autoantibody manufacturing. The human homologue of the mouse double minute 2 (MDM2) is effectively often called the detrimental regulator of p53. MDM2 has been reported to be overexpressed in SLE animal mannequin and to advertise SLE.
Since abnormally expressed proteins can induce autoimmune response, anti-MDM2 autoantibody was examined in SLE sufferers. Strategies. Anti-MDM2 antibody in sera from 43 SLE sufferers and 69 wholesome individuals was investigated by ELISA. Constructive samples had been additional confirmed by western blotting.
The immunological feathers of anti-MDM2 constructive sera had been analyzed by oblique immunofluorescence assay. Anti-p53 was additionally investigated in SLE sufferers by ELISA, and the correlation of anti-MDM2 and anti-p53 was analyzed. Outcomes.
The presence of anti-MDM2 in SLE sufferers was 23.30%, a lot larger than regular wholesome individuals (4.30%). These anti-MDM2 constructive sera current a nuclear staining sample. The presence of anti-p53 in SLE sufferers was 39.50%, and the titer of anti-MDM2 was positively correlated with anti-p53 in SLE sufferers. Conclusions. Anti-MDM2 autoantibody was detected at excessive prevalence in SLE sufferers. The detection of anti-MDM2 in SLE sufferers must be clinically helpful.
Mdm2 promotes systemic lupus erythematosus and lupus nephritis.
Systemic lupus erythematosus (SLE) is a polyclonal autoimmune syndrome directed towards a number of nuclear autoantigens. Though RNA and DNA appear to have equivalent immunostimulatory results on systemic and intrarenal irritation, every appears to vary with regard to the propensity to induce mitogenic results resembling lymphoproliferation.
To establish potential mechanisms by which DNA particularly contributes to the pathogenesis of lupus nephritis, we stimulated cells with immunostimulatory DNA or RNA in vitro and used microarray to match the transcriptomes of RNA- and DNA-induced genes. Immunostimulatory DNA, however not RNA, induced Mdm2, which is a detrimental regulator of p53. In vivo, we noticed better expression and activation of Mdm2 within the spleen and kidneys in a mouse mannequin of lupus (MRL-Fas(lpr) mice) than wholesome controls.
Therapy of MRL-Fas(lpr) mice with the Mdm2 inhibitor nutlin-3a prevented nephritis and lung illness and considerably extended survival. Inhibition of Mdm2 lowered systemic irritation and abrogated immune complicated illness by suppressing plasma cells and the manufacturing of lupus autoantibodies. As well as, nutlin-3a suppressed the irregular growth of all T cell subsets, together with CD3(+)CD4(-)CD8(-) T cells, which related to attenuated systemic irritation.
Nevertheless, inhibiting Mdm2 didn’t trigger myelosuppression or have an effect on splenic regulatory T cells, neutrophils, dendritic cells, or monocytes. Taken collectively, these information recommend that the induction of Mdm2 promotes the growth of plasma cells and CD3(+)CD4(-)CD8(-) T cells, which trigger autoantibody manufacturing and immune complicated illness in MRL-Fas(lpr) mice. Antagonizing Mdm2 might have therapeutic potential in lupus nephritis.
LDLRAD3 Antibody |
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| 1-CSB-PA007326 | Cusabio |
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Description: A polyclonal antibody against LDLRAD3. Recognizes LDLRAD3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: IF, ELISA;IF:1/200-1/1000.ELISA:1/40000 |
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LDLRAD3 Antibody |
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| CSB-PA786511- | Cusabio | each | EUR 402 |
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Description: A polyclonal antibody against LDLRAD3. Recognizes LDLRAD3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:500 |
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LDLRAD3 Antibody |
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| CSB-PA786511-100ul | Cusabio | 100ul | EUR 379.2 |
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Description: A polyclonal antibody against LDLRAD3. Recognizes LDLRAD3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:500 |
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LDLRAD3 Antibody |
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| C16505-100ul | Assay Biotech | 100μl | EUR 217 |
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Description: LDLRAD3 Rabbit Polyclonal Antibody |
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LDLRAD3 Antibody |
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| C16505-50ul | Assay Biotech | 50μl | EUR 143.5 |
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Description: LDLRAD3 Rabbit Polyclonal Antibody |
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LDLRAD3 Antibody |
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| E034765 | EnoGene | 100μg/100μl | EUR 255 |
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Description: Available in various conjugation types. |
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LDLRAD3 Antibody |
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| E11-16505C | EnoGene | 100μg | EUR 225 |
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Description: Available in various conjugation types. |
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LDLRAD3 Antibody |
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| E306476 | EnoGene | 100μg/200μl | EUR 275 |
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Description: Available in various conjugation types. |
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LDLRAD3 Antibody |
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| E38PA3456 | EnoGene | 100ul | EUR 225 |
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Description: Available in various conjugation types. |
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LDLRAD3 Antibody |
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| GWB-MT014E | GenWay Biotech | 50ug | Ask for price |
LDLRAD3 Antibody |
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| MBS5316390-01mL | MyBiosource | 0.1mL | EUR 470 |
LDLRAD3 Antibody |
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| MBS5316390-5x01mL | MyBiosource | 5x0.1mL | EUR 1955 |
LDLRAD3 Antibody |
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| MBS7131410-01mL | MyBiosource | 0.1mL | EUR 270 |
LDLRAD3 Antibody |
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| MBS7131410-5x01mL | MyBiosource | 5x0.1mL | EUR 1200 |
LDLRAD3 Antibody |
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| MBS7119053-005mg | MyBiosource | 0.05mg | EUR 150 |
LDLRAD3 Antibody |
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| MBS7119053-01mg | MyBiosource | 0.1mg | EUR 190 |
LDLRAD3 Antibody |
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| MBS7119053-5x01mg | MyBiosource | 5x0.1mg | EUR 845 |
LDLRAD3 Antibody |
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| MBS853245-01mg | MyBiosource | 0.1mg | EUR 305 |
LDLRAD3 Antibody |
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| MBS853245-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 465 |
LDLRAD3 Antibody |
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| MBS853245-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 465 |
LDLRAD3 Antibody |
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| MBS853245-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 465 |
LDLRAD3 Antibody |
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| MBS853245-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 465 |
LDLRAD3 Antibody |
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| MBS8581975-01mL | MyBiosource | 0.1mL | EUR 305 |
LDLRAD3 Antibody |
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| MBS8581975-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 465 |
LDLRAD3 Antibody |
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| MBS8581975-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 465 |
LDLRAD3 Antibody |
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| MBS8581975-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 465 |
LDLRAD3 Antibody |
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| MBS8581975-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 465 |
LDLRAD3 Antibody |
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| MBS858563-01mg | MyBiosource | 0.1mg | EUR 345 |
LDLRAD3 Antibody |
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| MBS858563-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 565 |
LDLRAD3 Antibody |
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| MBS858563-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 565 |
LDLRAD3 Antibody |
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| MBS858563-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 565 |
LDLRAD3 Antibody |
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| MBS858563-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 565 |
LDLRAD3 Antibody |
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| MBS9506488-005mL | MyBiosource | 0.05mL | EUR 285 |
LDLRAD3 Antibody |
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| MBS9506488-01mL | MyBiosource | 0.1mL | EUR 385 |
LDLRAD3 Antibody |
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| MBS9506488-5x01mL | MyBiosource | 5x0.1mL | EUR 1590 |
LDLRAD3 Antibody |
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| MBS9407445-01mL | MyBiosource | 0.1mL | EUR 420 |
LDLRAD3 Antibody |
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| MBS9407445-5x01mL | MyBiosource | 5x0.1mL | EUR 1740 |
LDLRAD3 Antibody |
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| MBS9408725-005mL | MyBiosource | 0.05mL | EUR 245 |
LDLRAD3 Antibody |
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| MBS9408725-01mL | MyBiosource | 0.1mL | EUR 305 |
LDLRAD3 Antibody |
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| MBS9408725-5x01mL | MyBiosource | 5x0.1mL | EUR 1230 |
LDLRAD3 Polyclonal Antibody |
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| ABP53840-003ml | Abbkine | 0.03ml | EUR 189.6 |
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Description: A polyclonal antibody for detection of LDLRAD3 from Human, Mouse. This LDLRAD3 antibody is for IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human LDLRAD3 at AA rangle: 10-90 |
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LDLRAD3 Polyclonal Antibody |
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| ABP53840-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of LDLRAD3 from Human, Mouse. This LDLRAD3 antibody is for IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human LDLRAD3 at AA rangle: 10-90 |
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LDLRAD3 Polyclonal Antibody |
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| ABP53840-02ml | Abbkine | 0.2ml | EUR 496.8 |
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Description: A polyclonal antibody for detection of LDLRAD3 from Human, Mouse. This LDLRAD3 antibody is for IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human LDLRAD3 at AA rangle: 10-90 |
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LDLRAD3 Polyclonal Antibody |
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| BT-AP04989-100ul | Jiaxing Korain Biotech Ltd (BT Labs) | 100ul | Ask for price |
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Description: LDLRAD3 (Low Density Lipoprotein Receptor Class A Domain Containing 3) is a Protein Coding gene. GO annotations related to this gene include beta-amyloid binding. An important paralog of this gene is LRP3. ay influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. |
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LDLRAD3 Polyclonal Antibody |
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| BT-AP04989-20ul | Jiaxing Korain Biotech Ltd (BT Labs) | 20ul | Ask for price |
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Description: LDLRAD3 (Low Density Lipoprotein Receptor Class A Domain Containing 3) is a Protein Coding gene. GO annotations related to this gene include beta-amyloid binding. An important paralog of this gene is LRP3. ay influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. |
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LDLRAD3 Polyclonal Antibody |
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| BT-AP04989-50ul | Jiaxing Korain Biotech Ltd (BT Labs) | 50ul | Ask for price |
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Description: LDLRAD3 (Low Density Lipoprotein Receptor Class A Domain Containing 3) is a Protein Coding gene. GO annotations related to this gene include beta-amyloid binding. An important paralog of this gene is LRP3. ay influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production. |
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LDLRAD3 Conjugated Antibody |
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| C34765 | SAB | 100ul | EUR 476.4 |
LDLRAD3 polyclonal antibody |
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| BS65108 | Bioworld Biotech | 50ul | EUR 275 |
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Description: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
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LDLRAD3 Polyclonal Antibody |
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| JOT-AP04989-100ul | Jotbody | 100ul | EUR 220 |
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Description: Human;Mouse |
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LDLRAD3 Polyclonal Antibody |
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| JOT-AP04989-50ul | Jotbody | 50ul | EUR 144 |
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Description: Human;Mouse |
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LDLRAD3 Polyclonal Antibody |
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| E20-72551 | EnoGene | 100ug | EUR 225 |
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Description: Available in various conjugation types. |
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LDLRAD3 Polyclonal Antibody |
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| E44H05159 | EnoGene | 100ul | EUR 255 |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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LDLRAD3 Polyclonal Antibody |
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| MBS8523532-01mg | MyBiosource | 0.1mg | EUR 305 |
LDLRAD3 Polyclonal Antibody |
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| MBS8523532-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 465 |
LDLRAD3 Polyclonal Antibody |
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| MBS8523532-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 465 |
LDLRAD3 Polyclonal Antibody |
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| MBS8523532-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 465 |
LDLRAD3 Polyclonal Antibody |
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| MBS8523532-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 465 |
LDLRAD3 Polyclonal Antibody |
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| MBS9236562-01mL | MyBiosource | 0.1mL | EUR 415 |
LDLRAD3 Polyclonal Antibody |
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| MBS9236562-5x01mL | MyBiosource | 5x0.1mL | EUR 1841 |
LDLRAD3 Conjugated Antibody |
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| MBS9445516-01mLAF350 | MyBiosource | 0.1mL(AF350) | EUR 480 |
LDLRAD3 Conjugated Antibody |
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| MBS9445516-01mLAF405 | MyBiosource | 0.1mL(AF405) | EUR 480 |
LDLRAD3 Conjugated Antibody |
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| MBS9445516-01mLAF488 | MyBiosource | 0.1mL(AF488) | EUR 480 |
LDLRAD3 Conjugated Antibody |
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| MBS9445516-01mLAF555 | MyBiosource | 0.1mL(AF555) | EUR 480 |
LDLRAD3 Conjugated Antibody |
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| MBS9445516-01mLBiotin | MyBiosource | 0.1mL(Biotin) | EUR 480 |
LDLRAD3 Polyclonal Antibody |
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| UB-GEN-13186 | UpingBio | 100 ul | EUR 200 |
LDLRAD3 Antibody (C-term) |
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| MBS9201207-008mL | MyBiosource | 0.08mL | EUR 210 |
LDLRAD3 Antibody (C-term) |
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| MBS9201207-04mL | MyBiosource | 0.4mL | EUR 430 |
LDLRAD3 Antibody (C-term) |
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| MBS9201207-5x04mL | MyBiosource | 5x0.4mL | EUR 1910 |
LDLRAD3 antibody - middle region |
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| MBS3211240-01mL | MyBiosource | 0.1mL | EUR 455 |
LDLRAD3 antibody - middle region |
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| MBS3211240-5x01mL | MyBiosource | 5x0.1mL | EUR 1995 |
LDLRAD3 Rabbit Polyclonal Antibody |
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| ES4839-100ul | ELK Biotech | 100ul | EUR 124 |
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Description: IF, ELISA |
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LDLRAD3 Rabbit Polyclonal Antibody |
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| ES4839-50ul | ELK Biotech | 50ul | EUR 74 |
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Description: IF, ELISA |
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OAAF03797-100UG - LDLRAD3 Antibody |
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| OAAF03797-100UG | Aviva Systems Biology | 100ug | EUR 329 |
Polyclonal LDLRAD3 antibody - middle region |
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| APR01194G | Leading Biology | 0.05mg | EUR 633.6 |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human LDLRAD3 - middle region. This antibody is tested and proven to work in the following applications: |
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LDLRAD3 Antibody (C-term) Blocking peptide |
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| MBS9218500-INQUIRE | MyBiosource | INQUIRE | Ask for price |
LDLRAD3 |
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| CSB-CL803154HU | Cusabio | 10 μg plasmid + 200μl Glycerol | Ask for price |
ARP53301_P050-25UL - LDLRAD3 Antibody - middle region |
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| ARP53301_P050-25UL | Aviva Systems Biology | 25ul | EUR 99 |
ARP53301_P050 - LDLRAD3 antibody - middle region (ARP53301_P050) |
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| ARP53301_P050 | Aviva Systems Biology | 100ul | EUR 389 |
LDLRAD3 (C-term) rabbit polyclonal antibody, Aff - Purified |
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| AP52462PU-N | Origene Technologies GmbH | 400 µl | Ask for price |
LDLRAD3 cDNA Clone |
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| MBS1271543-001mgPlasmid02mLGlycerolStock | MyBiosource | 0.01mgPlasmid+0.2mLGlycerol-Stock | EUR 355 |
LDLRAD3 cDNA Clone |
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| MBS1271543-5x001mgPlasmid5x02mLGlycerolStock | MyBiosource | 5x0.01mgPlasmid+5x0.2mLGlycerol-Stock | EUR 1565 |
Mouse LDLRAD3 siRNA |
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| 20-abx922395 | Abbexa |
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Human LDLRAD3 siRNA |
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| 20-abx922396 | Abbexa |
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LDLRAD3 siRNA (Mouse) |
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| MBS8202534-15nmol | MyBiosource | 15nmol | EUR 405 |
LDLRAD3 siRNA (Mouse) |
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| MBS8202534-30nmol | MyBiosource | 30nmol | EUR 565 |
LDLRAD3 siRNA (Mouse) |
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| MBS8202534-5x30nmol | MyBiosource | 5x30nmol | EUR 2450 |
LDLRAD3 siRNA (Human) |
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| MBS8235640-15nmol | MyBiosource | 15nmol | EUR 405 |
p53 standing dictates responses of B lymphomas to monotherapy with proteasome inhibitors.
The proapoptotic perform of p53 is assumed to underlie most anticancer modalities and can be activated in response to oncogenic insults, resembling overexpression of the Myc oncoprotein. Right here we generated tractable B lymphomas utilizing retroviral transduction of the MYC oncogene into hematopoietic cells with 2 knock-in alleles encoding a fusion between p53 and 4-hydroxytamoxifen (4OHT) receptor (p53ER(TAM)).
In these polyclonal tumors, Myc is the one oncogenic lesion, and p53ER(TAM) standing will be quickly toggled between “off” and “on” with 4OHT, supplied that the Trp53 promoter has been independently activated. Though 4OHT can set off widespread apoptosis and overt tumor regression even within the absence of DNA-damaging brokers, in tumors with excessive ranges of Mdm2 these responses are blunted.
Nevertheless, cotreatment with proteasome inhibitors absolutely restores therapeutic results in vivo. Equally, human Burkitt lymphomas with wild-type p53 and overexpression of Hdm2 are extremely delicate to proteasome inhibitors, except p53 ranges are lowered utilizing the HPV-E6 ubiquitin ligase. Due to this fact, proteasome inhibitors could possibly be extremely efficient as a monotherapy towards Myc-induced lymphomas, without having for adjuvant chemotherapy or radiation remedy. Then again, their efficacy is crucially depending on the wild-type p53 standing of the tumor, putting vital restrictions on affected person choice
Stat3 Antibody |
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| 3470R-100 | Biovision | each | EUR 379.2 |
Stat3 Antibody |
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| 3470R-30T | Biovision | each | EUR 175.2 |
STAT3 Antibody |
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| 48732 | SAB | 100ul | EUR 499 |
STAT3 Antibody |
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| 48732-100ul | SAB | 100ul | EUR 399.6 |
STAT3 Antibody |
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| 48732-50ul | SAB | 50ul | EUR 286.8 |
Stat3 Antibody |
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| 48780 | SAB | 100ul | EUR 499 |
Stat3 Antibody |
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| 48780-100ul | SAB | 100ul | EUR 399.6 |
Stat3 Antibody |
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| 48780-50ul | SAB | 50ul | EUR 286.8 |
STAT3 antibody |
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| 70R-35948 | Fitzgerald | 100 ug | EUR 420 |
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Description: Rabbit polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-37485 | Fitzgerald | 100 ug | EUR 260 |
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Description: Rabbit Polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-37486 | Fitzgerald | 100 ug | EUR 260 |
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Description: Rabbit Polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-50431 | Fitzgerald | 100 ul | EUR 286 |
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Description: Purified Polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-50432 | Fitzgerald | 100 ul | EUR 242 |
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Description: Purified Polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-50433 | Fitzgerald | 100 ul | EUR 242 |
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Description: Purified Polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-51642 | Fitzgerald | 100 ul | EUR 286 |
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Description: Purified Polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-31708 | Fitzgerald | 100 ug | EUR 294 |
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Description: Rabbit polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-32513 | Fitzgerald | 100 ug | EUR 294 |
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Description: Rabbit polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-32515 | Fitzgerald | 100 ug | EUR 294 |
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Description: Rabbit polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-20573 | Fitzgerald | 50 ul | EUR 289 |
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Description: Rabbit polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-11848 | Fitzgerald | 100 ug | EUR 343 |
|
Description: Rabbit polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-13773 | Fitzgerald | 100 ug | EUR 386.4 |
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Description: Affinity purified Rabbit polyclonal STAT3 antibody |
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STAT3 antibody |
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| 70R-14315 | Fitzgerald | 100 ug | EUR 519 |
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Description: Affinity purified Rabbit polyclonal STAT3 antibody |
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STAT3 Antibody |
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| 43315 | SAB | 100ul | EUR 319 |
STAT3 Antibody |
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| 43315-100ul | SAB | 100ul | EUR 302.4 |
STAT3 Antibody |
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| 7197-002mg | ProSci | 0.02 mg | EUR 206.18 |
|
Description: STAT3 Antibody: STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, and STAT6), STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile. STAT3 signals are pivotal to the proliferation and differentiation of neural stem cells and also participate in neuronal regeneration and cancers of the nervous system. |
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STAT3 Antibody |
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| 7197-01mg | ProSci | 0.1 mg | EUR 523.7 |
|
Description: STAT3 Antibody: STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (STAT1, STAT2, STAT3, STAT4, STAT5a, STAT5b, and STAT6), STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile. STAT3 signals are pivotal to the proliferation and differentiation of neural stem cells and also participate in neuronal regeneration and cancers of the nervous system. |
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STAT3 Antibody |
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| ABF5205 | Lifescience Market | 100 ug | EUR 525.6 |
STAT3 Antibody |
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| ABF6293 | Lifescience Market | 100 ug | EUR 525.6 |
STAT3 Antibody |
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| ABF6294 | Lifescience Market | 100 ug | EUR 525.6 |
STAT3 Antibody |
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| ABF6295 | Lifescience Market | 100 ug | EUR 525.6 |
STAT3 antibody |
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| 10R-1224 | Fitzgerald | 100 ug | EUR 543 |
|
Description: Mouse monoclonal STAT3 antibody |
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Stat3 antibody |
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| 20R-1593 | Fitzgerald | 100 ug | EUR 807.6 |
|
Description: Rabbit polyclonal Stat3 antibody |
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Stat3 antibody |
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| 20R-1597 | Fitzgerald | 100 ug | EUR 846 |
|
Description: Rabbit polyclonal Stat3 antibody |
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STAT3 antibody |
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| 20R-1911 | Fitzgerald | 50 ug | EUR 269 |
|
Description: Rabbit polyclonal STAT3 antibody |
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STAT3 antibody |
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| 20R-1912 | Fitzgerald | 50 ug | EUR 269 |
|
Description: Rabbit polyclonal STAT3 antibody |
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STAT3 antibody |
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| 20R-2227 | Fitzgerald | 50 ug | EUR 269 |
|
Description: Rabbit polyclonal STAT3 antibody |
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STAT3 antibody |
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| 20R-2228 | Fitzgerald | 50 ug | EUR 269 |
|
Description: Rabbit polyclonal STAT3 antibody |
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STAT3 antibody |
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| 10R-2073 | Fitzgerald | 100 ul | EUR 468 |
|
Description: Mouse monoclonal STAT3 antibody |
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STAT3 antibody |
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| 10R-2269 | Fitzgerald | 100 ul | EUR 468 |
|
Description: Mouse monoclonal STAT3 antibody |
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STAT3 antibody |
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| 10R-5956 | Fitzgerald | 100 ul | EUR 709 |
|
Description: Mouse monoclonal STAT3 antibody |
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STAT3 Antibody |
|||
| 1-CSB-PA004173 | Cusabio |
|
|
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Description: A polyclonal antibody against STAT3. Recognizes STAT3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/5000 |
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STAT3 Antibody |
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| 1-CSB-PA004174 | Cusabio |
|
|
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Description: A polyclonal antibody against STAT3. Recognizes STAT3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/10000 |
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Stat3 Antibody |
|||
| B7223-100ul | Assay Biotech | 100μl | EUR 217 |
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Description: Stat3 Rabbit Polyclonal Antibody |
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Stat3 Antibody |
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| B7223-50ul | Assay Biotech | 50μl | EUR 143.5 |
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Description: Stat3 Rabbit Polyclonal Antibody |
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Stat3 Antibody |
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| B7224-100ul | Assay Biotech | 100μl | EUR 217 |
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Description: Stat3 Rabbit Polyclonal Antibody |
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Stat3 Antibody |
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| B7224-50ul | Assay Biotech | 50μl | EUR 143.5 |
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Description: Stat3 Rabbit Polyclonal Antibody |
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STAT3 Antibody |
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| BF0354 | Affbiotech | 200ul | EUR 540 |
STAT3 Antibody |
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| BF0354-100ul | Affinity Biosciences | 100ul | EUR 210 |
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Description: WB,IHC,IF/ICC,ELISA |
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STAT3 Antibody |
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| BF0354-200ul | Affinity Biosciences | 200ul | EUR 270 |
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Description: WB,IHC,IF/ICC,ELISA |
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STAT3 Antibody |
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| BF0354-50ul | Affinity Biosciences | 50ul | EUR 150 |
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Description: WB,IHC,IF/ICC,ELISA |
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STAT3 Antibody |
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| AF5205 | Affbiotech | 200ul | EUR 420 |
STAT3 Antibody |
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| AF5205-100ul | Affinity Biosciences | 100ul | EUR 168 |
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Description: WB,IF/ICC,ELISA(peptide) |
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STAT3 Antibody |
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| AF5205-200ul | Affinity Biosciences | 200ul | EUR 210 |
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Description: WB,IF/ICC,ELISA(peptide) |
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STAT3 Antibody |
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| AF6293 | Affbiotech | 200ul | EUR 420 |
STAT3 Antibody |
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| AF6293-100ul | Affinity Biosciences | 100ul | EUR 168 |
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Description: WB,IHC,IF/ICC,ELISA(peptide) |
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STAT3 Antibody |
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| AF6293-200ul | Affinity Biosciences | 200ul | EUR 210 |
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Description: WB,IHC,IF/ICC,ELISA(peptide) |
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STAT3 Antibody |
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| AF6294 | Affbiotech | 200ul | EUR 420 |
STAT3 Antibody |
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| AF6294-100ul | Affinity Biosciences | 100ul | EUR 168 |
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Description: WB,IHC,IF/ICC,ELISA(peptide) |
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STAT3 Antibody |
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| AF6294-200ul | Affinity Biosciences | 200ul | EUR 210 |
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Description: WB,IHC,IF/ICC,ELISA(peptide) |
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STAT3 Antibody |
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| AF6295 | Affbiotech | 200ul | EUR 420 |
STAT3 Antibody |
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| AF6295-100ul | Affinity Biosciences | 100ul | EUR 168 |
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Description: WB,IHC,IF/ICC,ELISA(peptide) |
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STAT3 Antibody |
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| AF6295-200ul | Affinity Biosciences | 200ul | EUR 210 |
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Description: WB,IHC,IF/ICC,ELISA(peptide) |
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STAT3 Antibody |
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| AF7800 | Affbiotech | 200ul | EUR 540 |
STAT3 Antibody |
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| AF7800-100ul | Affinity Biosciences | 100ul | EUR 210 |
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Description: WB,ELISA(peptide) |
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STAT3 Antibody |
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| AF7800-200ul | Affinity Biosciences | 200ul | EUR 270 |
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Description: WB,ELISA(peptide) |
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STAT3 Antibody |
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| AF7800-50ul | Affinity Biosciences | 50ul | EUR 150 |
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Description: WB,ELISA(peptide) |
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Stat3 Antibody |
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| C10589-100ul | Assay Biotech | 100μl | EUR 217 |
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Description: Stat3 Rabbit Polyclonal Antibody |
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Stat3 Antibody |
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| C10589-50ul | Assay Biotech | 50μl | EUR 143.5 |
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Description: Stat3 Rabbit Polyclonal Antibody |
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STAT3 antibody |
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| CAF50341-100ug | Biomatik Corporation | 100ug | EUR 338 |
STAT3 Antibody |
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| CAC08876-100ug | Biomatik Corporation | 100ug | EUR 314 |
STAT3 Antibody |
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| CAC08876-50ug | Biomatik Corporation | 50ug | EUR 199.2 |
STAT3 Antibody |
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| 1-CSB-PA022812GA01HU | Cusabio |
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|
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Description: A polyclonal antibody against STAT3. Recognizes STAT3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB |
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STAT3 Antibody |
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| 1-CSB-PA022812LA01HU | Cusabio |
|
|
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Description: A polyclonal antibody against STAT3. Recognizes STAT3 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF, IP; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500, IP:1:200-1:2000 |
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Stat3 Antibody |
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| CSB-PA022812XA01MO-02mg | Cusabio | 0.2mg | Ask for price |
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Description: Recombinant Mus musculus (Mouse) Stat3 protein |
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Stat3 Antibody |
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| CSB-PA022812XA01MO-10mg | Cusabio | 10mg | Ask for price |
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Description: Recombinant Mus musculus (Mouse) Stat3 protein |
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STAT3 Antibody |
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| 1-CSB-PA050164 | Cusabio |
|
|
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Description: A polyclonal antibody against STAT3. Recognizes STAT3 from Human, Mouse, Rat, Monkey. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000 |
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STAT3 Antibody |
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| 1-CSB-PA080245 | Cusabio |
|
|
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Description: A polyclonal antibody against STAT3. Recognizes STAT3 from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC;WB:1:1000-2000.IHC:1:200-500 |
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STAT3 Antibody |
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| GWB-98F230 | GenWay Biotech | 0.1 ml | Ask for price |
STAT3, Antibody |
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| GWB-F0B151 | GenWay Biotech | 1 ml | Ask for price |
STAT3 Antibody |
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| GWB-ML023E | GenWay Biotech | 50ug | Ask for price |
STAT3, Antibody |
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| GWB-260839 | GenWay Biotech | 7 ml | Ask for price |
STAT3 Antibody |
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| GWB-MX425B | GenWay Biotech | 50ug | Ask for price |
STAT3 Antibody |
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| GWB-MM719H | GenWay Biotech | 50ug | Ask for price |
STAT3 Antibody |
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| GWB-17B4D9 | GenWay Biotech | 0.5 ml | Ask for price |
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